Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

Effects of Blueberry Consumption on Fecal Microbiome Composition and Circulating Metabolites, Lipids, and Lipoproteins in a Randomized Controlled Trial of Older Adults with Overweight or Obesity: The BEACTIVE Trial

Porter Starr KN, Connelly MA, Wallis J, North R, Zhang Q, Song K, Gonzalez-Delgado JM, Brochu HN, Icenhour CR, Iyer LK, Miller MG, Huffman KM, Kraus WE, Bales CW.
Nutrients. 2025 17(7):1200.
Read More

Scientific Evidence for the Beneficial Effects of Dietary Blueberries on Gut Health: A Systematic Review

Della Lucia CM, Oliveira LA, Dias KA, Pereira SMS, da Conceicao AR, Anandh Babu PV.
Read More

Blueberries Improve Abdominal Symptoms, Well-Being and Functioning in Patients with Functional Gastrointestinal Disorders

Wilder-Smith CH, Materna A, Olesen SS
Nutrients. 2023 May 20;15(10):2396. doi: 10.3390/nu15102396.
Read More

Lactobacillus johnsonii N6.2 and Blueberry Phytophenols Affect Lipidome and Gut Microbiota Composition of Rats Under High-Fat Diet

Leandro Dias Teixeira, Monica F Torrez Lamberti, Evon DeBose-Scarlett, Erol Bahadiroglu, Timothy J Garrett, Christopher L Gardner, Julie L Meyer, Graciela L Lorca, Claudio F Gonzalez
Front Nutr . 2021 Oct 14;8:757256. doi: 10.3389/fnut.2021.757256.
Read More

Impact of blueberry consumption on the human fecal bileacidome: A pilot study of bile acid modulation by freeze-dried blueberry. 

William Gagnon, Véronique Garneau, Jocelyn Trottier, Mélanie Verreault, Charles Couillard, Denis Roy, André Marette, Jean-Philippe Drouin-Chartier, Marie-Claude Vohl, Olivier Barbier
Nutrients. 2022; 14(18):3857.
Read More

Blueberry polyphenols alter gut microbiota & phenolic metabolism in rats

Dennis P Cladis, Abigayle M R Simpson, Kaitlyn J Cooper, Cindy H Nakatsu, Mario G Ferruzzi, Connie M Weaver
Food Funct. 2021 Mar 21;12(6):2442-2456.
Read More

Anti-adhesive activity of a Vaccinium corymbosum polyphenolic extract targeting intestinal colonization by Klebsiella pneumoniae

Eva Gato, Alicja Rosalowska, Marta Martínez-Guitián, Marta Lores, German Bou, Astrid Pérez
Biomed Pharmacother . 2020 Dec;132:110885.
Read More

Whole Blueberry and Isolated Polyphenol-Rich Fractions Modulate Specific Gut Microbes in an In Vitro Colon Model and in a Pilot Study in Human Consumers

Alexandra Ntemiri, Tarini S Ghosh, Molly E Gheller, Tam T T Tran, Jamie E Blum, Paola Pellanda, Klara Vlckova, Marta C Neto, Amy Howell, Anna Thalacker-Mercer, Paul W O'Toole
Nutrients . 2020 Sep 12;12(9):2800.
Read More

Valorization of Persimmon and Blueberry Byproducts to Obtain Functional Powders: In Vitro Digestion and Fermentation by Gut Microbiota

Claudia Bas-Bellver, Cristina Andrés, Lucía Seguí, Cristina Barrera, Nuria Jiménez-Hernández, Alejandro Artacho, Noelia Betoret, María José Gosalbes
J Agric Food Chem . 2020 Jul 29;68(30):8080-8090.
Read More