Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

Blueberries Improve Abdominal Symptoms, Well-Being and Functioning in Patients with Functional Gastrointestinal Disorders

Wilder-Smith CH, Materna A, Olesen SS
Nutrients. 2023 May 20;15(10):2396. doi: 10.3390/nu15102396.
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Change in habitual intakes of flavonoid-rich foods and mortality in US males and females

Nicola P Bondonno , Yan Lydia Liu, Yan Zheng, Kerry Ivey, Walter C Willett, Meir J Stampfer, Eric B Rimm , Aedín Cassidy
BMC Med. 2023 May 12;21(1):181. doi: 10.1186/s12916-023-02873-z.
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Daily Blueberry Consumption for 12 Weeks Improves Endothelial Function in Postmenopausal Women with Above-Normal Blood Pressure through Reductions in Oxidative Stress: A Randomized Controlled Trial

E. K. Woolf, J. D. Terwoord, N. S. Litwin, A. R. Vazquez, S. Y. Lee, N. Ghanem, K. A. Michell, B. T. Smith, L. E. Grabos, N. B. Ketelhut, N. P. Bachman, M. E. Smith, M. Le Sayec, S. Rao, C. Gentile, T. L. Weir, A. Rodriguez-Mateos, D.R. Seals, F. A. Dinenno and S. A. Johnson
Food Funct., 2023, DOI: 10.1039/D3FO00157A
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An 8-week freeze-dried blueberry supplement impacts immune-related pathways: a randomized, double-blind placebo-controlled trial

Michèle Rousseau, Justine Horne, Frédéric Guénard, Juan de Toro-Martín, Véronique Garneau, Valérie Guay, Michèle Kearney, Geneviève Pilon, Denis Roy, Patrick Couture, Charles Couillard, André Marette, Marie-Claude Vohl
Genes Nutr . 2021 May 17;16(1):7. doi: 10.1186/s12263-021-00688-2
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Lactobacillus johnsonii N6.2 and Blueberry Phytophenols Affect Lipidome and Gut Microbiota Composition of Rats Under High-Fat Diet

Leandro Dias Teixeira, Monica F Torrez Lamberti, Evon DeBose-Scarlett, Erol Bahadiroglu, Timothy J Garrett, Christopher L Gardner, Julie L Meyer, Graciela L Lorca, Claudio F Gonzalez
Front Nutr . 2021 Oct 14;8:757256. doi: 10.3389/fnut.2021.757256.
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Comparative Phytochemical Profiles and Antioxidant Enzyme Activity Analyses of the Southern Highbush Blueberry ( Vaccinium corymbosum) at Different Developmental Stages

Yueting Sun, Min Li, Sangeeta Mitra, Rizwan Hafiz Muhammad, Biswojit Debnath, Xiaocao Lu, Hongxiang Jian, Dongliang Qiu
Molecules. 2018 Aug 31;23(9):2209. doi: 10.3390/molecules23092209.
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Blueberry benefits to cognitive function across the lifespan

Lynne Bell, Claire M Williams
Int J Food Sci Nutr . 2021 Aug;72(5):650-652. doi: 10.1080/09637486.2020.1852192.
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Effect of blueberry (Vaccinium virgatum) extract on depressive-like behavior and metabolic serum alterations in lipopolysaccharide-challenged mice

Solange Vega Custódio, Luiza Spohr, Natália Pontes Bona, Anita Avila de Souza, Bernardo de Moraes Meine, Sara Keske, Karina Pereira Luduvico, Fernando Lopez Alvez, Roselia Maria Spanevello, Francieli Moro Stefanello, Mayara Sandrielly Pereira Soares
J Food Biochem . 2021 Oct;45(10):e13920. doi: 10.1111/jfbc.13920
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Impact of blueberry consumption on the human fecal bileacidome: A pilot study of bile acid modulation by freeze-dried blueberry. 

William Gagnon, Véronique Garneau, Jocelyn Trottier, Mélanie Verreault, Charles Couillard, Denis Roy, André Marette, Jean-Philippe Drouin-Chartier, Marie-Claude Vohl, Olivier Barbier
Nutrients. 2022; 14(18):3857.
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Blueberry Supplementation in Midlife for Dementia Risk Reduction

Robert Krikorian, Matthew R. Skelton, Suzanne S. Summer, Marcelle D. Shidler, Patrick G. Sullivan
Nutrients. 2022 Apr 13; 14(8):1619
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