Scientific Research


The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Browse the research topics below to view the collection of in-depth blueberry science, and explore the following overview of research specifically funded by the USHBC.

Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) study: Rationale, design and baseline characteristics of a randomized control trial of the MIND diet on cognitive decline

Xiaoran Liu, Martha Clare Morris, Klodian Dhana, Jennifer Ventrelle, Kathleen Johnson, Louise Bishop, Chiquia S Hollings, Adrianna Boulin, Nancy Laranjo, Benjamin J Stubbs, Xavier Reilly, Vincent J Carey, Yamin Wang, Jeremy D Furtado, Santica M Marcovina, Christy Tangney, Neelum T Aggarwal, Konstantinos Arfanakis, Frank M Sacks, Lisa L Barnes
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Blueberry phenolics are associated with cognitive enhancement in supplemented healthy older adults

Grant A Rutledge, Amandeep K Sandhu, Marshall G Miller, Indika Edirisinghe, Britt B Burton-Freeman, Barbara Shukitt-Hale
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Blueberry phenolics are associated with cognitive enhancement in supplemented healthy older adults

Rutledge GA, Sandhu AK, Miller MG, Edirisinghe I, Burton-Freeman BB, Shukitt-Hale B.
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Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation

J A Joseph, B Shukitt-Hale, N A Denisova, D Bielinski, A Martin, J J McEwen, P C Bickford
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Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats

P C Bickford, T Gould, L Briederick, K Chadman, A Pollock, D Young, B Shukitt-Hale, J Joseph
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Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model

J A Joseph, N A Denisova, G Arendash, M Gordon, D Diamond, B Shukitt-Hale, D Morgan
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Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats

Gemma Casadesus, Barbara Shukitt-Hale, Heather M Stellwagen, Xiongwei Zhu, Hyoung-Gon Lee, Mark A Smith, James A Joseph
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Blueberry supplemented diet: effects on object recognition memory and nuclear factor-kappa B levels in aged rats

Pilar Goyarzu, David H Malin, Francis C Lau, Giulio Taglialatela, William D Moon, Ryan Jennings, Edward Moy, Deborah Moy, Stephen Lippold, Barbara Shukitt-Hale, James A Joseph
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