Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

Blueberry opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activation protein kinase

Yuyan Zhu, Paula C Bickford, Paul Sanberg, Brian Giunta, Jun Tan
Rejuvenation Res . 2008 Oct;11(5):891-901.
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Beneficial effects of berry fruit polyphenols on neuronal and behavioral aging

Lau, F.C. Search author for Lau, F.C. , Shukitt-Hale, B., Joseph, J.A.
Journal of the science of food and agriculture, v. 86,.14 pp. 2251.
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Cellular antioxidant activity of common fruits

Kelly L Wolfe, Xinmei Kang, Xiangjiu He, Mei Dong, Qingyuan Zhang, Rui Hai Liu
J Agric Food Chem . 2008 Sep 24;56(18):8418-26.
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Organ-specific distribution of phenolic compounds in bilberry (Vaccinium myrtillus) and ‘northblue’ blueberry (Vaccinium corymbosum x V. angustifolium)

Riihinen, Kaisu, Jaakola, Laura, Kärenlampi, Sirpa, Hohtola, Anja
Food chemistry, v. 110,.1 pp. 156-160. doi: 10.1016/j.foodchem.2008.01.057
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Blueberry-enriched diet ameliorates age-related declines in NMDA receptor-dependent LTP

Steven J Coultrap, Paula C Bickford, Michael D Browning
Age (Dordr) . 2008 Dec;30(4):263-72.
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Phenolic profile and antioxidant activity of highbush blueberry (Vaccinium corymbosum L.) during fruit maturation and ripening

Castrejón, Alejandro David Rodarte, Eichholz, Ines, Rohn, Sascha, Kroh, Lothar W., Huyskens-Keil, Susanne
Food chemistry, v. 109,.3 pp. 564-572. doi: 10.1016/j.foodchem.2008.01.007
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Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus

Barbara Shukitt-Hale, Francis C Lau, Amanda N Carey, Rachel L Galli, Edward L Spangler, Donald K Ingram, James A Joseph
Nutr Neurosci . 2008 Aug;11(4):172-82.
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Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels

Claire M Williams, Manal Abd El Mohsen, David Vauzour, Catarina Rendeiro, Laurie T Butler, Judi A Ellis, Matthew Whiteman, Jeremy P E Spencer
Free Radic Biol Med . 2008 Aug 1;45(3):295-305.
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Fruit quality, antioxidant capacity, and flavonoid content of organically and conventionally grown blueberries

Shiow Y Wang, Chi-Tsun Chen, William Sciarappa, Chien Y Wang, Mary J Camp
J Agric Food Chem . 2008 Jul 23;56(14):5788-94. doi: 10.1021/jf703775r.
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Effect of Vaccinium ashei reade leaves on lipid metabolism in Otsuka Long-Evans Tokushima Fatty rats

Koji Nagao, Kouki Higa, Bungo Shirouchi, Saori Nomura, Nao Inoue, Masashi Inafuku, Teruyoshi Yanagita
Biosci Biotechnol Biochem . 2008 Jun;72(6):1619-22.
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