Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

Dietary supplementation with blueberry extract improves survival of transplanted dopamine neurons

Susan O McGuire, Caryl E Sortwell, Barbara Shukitt-Hale, James A Joseph, Matthew J Hejna, Timothy J Collier
Nutr Neurosci. 2006 Oct-Dec;9(5-6):251-8.
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Protective activities of Vaccinium antioxidants with potential relevance to mitochondrial dysfunction and neurotoxicity

Yu Yao, Amandio Vieira
Neurotoxicology . 2007 Jan;28(1):93-100.
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Absorption of anthocyanins from blueberry extracts by caco-2 human intestinal cell monolayers

Weiguang Yi, Casimir C Akoh, Joan Fischer, Gerard Krewer
J Agric Food Chem . 2006 Jul 26;54(15):5651-8.
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Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging

Barbara Shukitt-Hale, Amanda N Carey, Daniel Jenkins, Bernard M Rabin, James A Joseph
Neurobiol Aging . 2007 Aug;28(8):1187-94.
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Behavioral and genoprotective effects of Vaccinium berries intake in mice

Daniela Barros, Olavo B Amaral, Ivan Izquierdo, Laura Geracitano, Maria do Carmo Bassols Raseira, Amélia Teresinha Henriques, Maria Rosana Ramirez
Pharmacol Biochem Behav . 2006 Jun;84(2):229-34.
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Effects of phenolic compounds in blueberries and muscadine grapes on HepG2 cell viability and apoptosis

Yi, W. Search author for Yi, W. , Akoh, C.C., Fischer, J., Krewer, G.
Food research international, v. 39,.5 pp. 628-638.
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Concentrations of anthocyanins in common foods in the United States and estimation of normal consumption

Xianli Wu, Gary R Beecher, Joanne M Holden, David B Haytowitz, Susan E Gebhardt, Ronald L Prior
J Agric Food Chem . 2006 May 31;54(11):4069-75.
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In vitro antileukaemic activity of extracts from berry plant leaves against sensitive and multidrug resistant HL60 cells

Katarzyna Skupień, Jan Oszmiański, Dorota Kostrzewa-Nowak, Jolanta Tarasiuk
Cancer Lett . 2006 May 18;236(2):282-91.
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Blueberry extract alters oxidative stress-mediated signaling in COS-7 cells transfected with selectively vulnerable muscarinic receptor subtypes

J A Joseph, D R Fisher, D Bielinski
J Alzheimers Dis . 2006 Mar;9(1):35-42.
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Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans

Mark A Wilson, Barbara Shukitt-Hale, Wilhelmina Kalt, Donald K Ingram, James A Joseph, Catherine A Wolkow
Aging Cell . 2006 Feb;5(1):59-68.
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