Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

In vitro antileukaemic activity of extracts from berry plant leaves against sensitive and multidrug resistant HL60 cells

Katarzyna Skupień, Jan Oszmiański, Dorota Kostrzewa-Nowak, Jolanta Tarasiuk
Cancer Lett . 2006 May 18;236(2):282-91.
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Blueberry extract alters oxidative stress-mediated signaling in COS-7 cells transfected with selectively vulnerable muscarinic receptor subtypes

J A Joseph, D R Fisher, D Bielinski
J Alzheimers Dis . 2006 Mar;9(1):35-42.
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Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans

Mark A Wilson, Barbara Shukitt-Hale, Wilhelmina Kalt, Donald K Ingram, James A Joseph, Catherine A Wolkow
Aging Cell . 2006 Feb;5(1):59-68.
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Blueberry supplemented diet reverses age-related decline in hippocampal HSP70 neuroprotection

Rachel L Galli, Donna F Bielinski, Aleksandra Szprengiel, Barbara Shukitt-Hale, James A Joseph
Neurobiol Aging . 2006 Feb;27(2):344-50.
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Differential effects of blueberry proanthocyanidins on androgen sensitive and insensitive human prostate cancer cell lines

Barbara M Schmidt, John W Erdman Jr, Mary Ann Lila
Cancer Lett . 2006 Jan 18;231(2):240-6.
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The beneficial effects of fruit polyphenols on brain aging

Francis C Lau, Barbara Shukitt-Hale, James A Joseph
Neurobiol Aging . 2005 Dec;26 Suppl 1:128-32.
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Blueberry- and spirulina-enriched diets enhance striatal dopamine recovery and induce a rapid, transient microglia activation after injury of the rat nigrostriatal dopamine system

Ingrid Strömberg, Carmelina Gemma, Jennifer Vila, Paula C Bickford
Exp Neurol . 2005 Dec;196(2):298-307.
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Phenolic compounds from blueberries can inhibit colon cancer cell proliferation and induce apoptosis

Weiguang Yi, Joan Fischer, Gerard Krewer, Casimir C Akoh
J Agric Food Chem . 2005 Sep 7;53(18):7320-9.
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Effect of lyophilised Vaccinium berries on memory, anxiety and locomotion in adult rats

Maria Rosana Ramirez, Ivan Izquierdo, Maria do Carmo Bassols Raseira, José Angelo Zuanazzi, Daniela Barros, Amélia Teresinha Henriques
Pharmacol Res . 2005 Dec;52(6):457-62.
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Flavonol glycosides and antioxidant capacity of various blackberry and blueberry genotypes determined by high-performance liquid chromatography/mass spectrometry

Cho, M.J., Howard, L.R., Prior, R.L., Clark, J.R.
Journal of the science of food and agriculture, v. 85,.13 pp. 2149.
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