Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

Berries and Steps: a protocol of a randomized, placebo-controlled pilot study testing freeze-dried blueberry powder in sedentary older adults with mild depressive symptoms

Millar CL, Wolfe A, Baldyga K, Dufour AB, Lipsitz LA
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Effect of replacing commonly consumed fruit in the United States with berries in the USDA healthy Dietary Patterns: a modeling analysis

Stote KS, Crowe-White K, Wada L.
Ann Med. 2025 Dec;57(1):2517817.
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Rationale and design of a randomized controlled trial evaluating the effects of blueberry consumption versus placebo on brain health in older adults

Uttke Z, Gabriel O, Smith C, Guardino ET, Mukamal K, Djousse L.
Contemp Clin Trials. 2025 Apr 27;154:107926.
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Bioavailability and pharmacokinetics of (poly)phenols following consumption of selected blueberries and a blueberry-rich protein bar by adult males and females: a randomized, crossover, controlled trial

Santana MC, Rathore AS, Chandra P, Everhart JL, Schulz H, Granillo CD, Ferruzzi MG, Iorizzo M, Lila MA, Diaz JT, Kay CD
Am J Clin Nutr. 121:779-794.
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Effects of Blueberry Consumption on Fecal Microbiome Composition and Circulating Metabolites, Lipids, and Lipoproteins in a Randomized Controlled Trial of Older Adults with Overweight or Obesity: The BEACTIVE Trial

Porter Starr KN, Connelly MA, Wallis J, North R, Zhang Q, Song K, Gonzalez-Delgado JM, Brochu HN, Icenhour CR, Iyer LK, Miller MG, Huffman KM, Kraus WE, Bales CW.
Nutrients. 2025 17(7):1200.
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Associations between flavonoid-rich food and flavonoid intakes and incident unhealthy aging outcomes in older United States males and females

Bondonno NP, Liu LP, Grodstein F, Rimm EB, Cassidy A
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A serving of blueberry (Vaccinium corymbosum) improves peripheral vascular function but not metabolic and functional markers in older subjects: A randomized, controlled, crossover study

Tucci M, Del Bo C, Martini D, Perna S, Marino M, Rendine M, Gardana C, Battezzati A, Leone A, Bertoli S, Aldini G, Riso P.
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Flavonoid-Rich Fruit Intake in Midlife and Late-Life and Associations with Risk of Dementia: The Framingham Heart Study

C. Lyu, P. F. Jacques, P. M. Doraiswamy, B. Young, A. S. Gurnani, R. Au & Phillip H. Hwang
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The state of the science on the health benefits of blueberries: a perspective

April J. Stull, Aedín Cassidy, Luc Djousse, Sarah A. Johnson, Robert Krikorian, Johanna W. Lampe, Kenneth J. Mukamal, David C. Nieman, Kathryn N. Porter Starr, Heather Rasmussen, Eric B. Rimm, Kim S. Stote, Christy Tangney
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Intake of Blueberries, Anthocyanins, and Risk of Eye Disease in Women

Howard D Sesso, Susanne Rautiainen, Sarah Jaehwa Park, Eunjung Kim, I-Min Lee, Robert J Glynn, Julie E Buring, William G Christen
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