Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

Daily Blueberry Consumption for 12 Weeks Improves Endothelial Function in Postmenopausal Women with Above-Normal Blood Pressure through Reductions in Oxidative Stress: A Randomized Controlled Trial

E. K. Woolf, J. D. Terwoord, N. S. Litwin, A. R. Vazquez, S. Y. Lee, N. Ghanem, K. A. Michell, B. T. Smith, L. E. Grabos, N. B. Ketelhut, N. P. Bachman, M. E. Smith, M. Le Sayec, S. Rao, C. Gentile, T. L. Weir, A. Rodriguez-Mateos, D.R. Seals, F. A. Dinenno and S. A. Johnson
Food Funct., 2023, DOI: 10.1039/D3FO00157A
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An 8-week freeze-dried blueberry supplement impacts immune-related pathways: a randomized, double-blind placebo-controlled trial

Michèle Rousseau, Justine Horne, Frédéric Guénard, Juan de Toro-Martín, Véronique Garneau, Valérie Guay, Michèle Kearney, Geneviève Pilon, Denis Roy, Patrick Couture, Charles Couillard, André Marette, Marie-Claude Vohl
Genes Nutr . 2021 May 17;16(1):7. doi: 10.1186/s12263-021-00688-2
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Lactobacillus johnsonii N6.2 and Blueberry Phytophenols Affect Lipidome and Gut Microbiota Composition of Rats Under High-Fat Diet

Leandro Dias Teixeira, Monica F Torrez Lamberti, Evon DeBose-Scarlett, Erol Bahadiroglu, Timothy J Garrett, Christopher L Gardner, Julie L Meyer, Graciela L Lorca, Claudio F Gonzalez
Front Nutr . 2021 Oct 14;8:757256. doi: 10.3389/fnut.2021.757256.
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Comparative Phytochemical Profiles and Antioxidant Enzyme Activity Analyses of the Southern Highbush Blueberry ( Vaccinium corymbosum) at Different Developmental Stages

Yueting Sun, Min Li, Sangeeta Mitra, Rizwan Hafiz Muhammad, Biswojit Debnath, Xiaocao Lu, Hongxiang Jian, Dongliang Qiu
Molecules. 2018 Aug 31;23(9):2209. doi: 10.3390/molecules23092209.
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Blueberry benefits to cognitive function across the lifespan

Lynne Bell, Claire M Williams
Int J Food Sci Nutr . 2021 Aug;72(5):650-652. doi: 10.1080/09637486.2020.1852192.
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Effect of blueberry (Vaccinium virgatum) extract on depressive-like behavior and metabolic serum alterations in lipopolysaccharide-challenged mice

Solange Vega Custódio, Luiza Spohr, Natália Pontes Bona, Anita Avila de Souza, Bernardo de Moraes Meine, Sara Keske, Karina Pereira Luduvico, Fernando Lopez Alvez, Roselia Maria Spanevello, Francieli Moro Stefanello, Mayara Sandrielly Pereira Soares
J Food Biochem . 2021 Oct;45(10):e13920. doi: 10.1111/jfbc.13920
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Impact of blueberry consumption on the human fecal bileacidome: A pilot study of bile acid modulation by freeze-dried blueberry. 

William Gagnon, Véronique Garneau, Jocelyn Trottier, Mélanie Verreault, Charles Couillard, Denis Roy, André Marette, Jean-Philippe Drouin-Chartier, Marie-Claude Vohl, Olivier Barbier
Nutrients. 2022; 14(18):3857.
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Blueberry Supplementation in Midlife for Dementia Risk Reduction

Robert Krikorian, Matthew R. Skelton, Suzanne S. Summer, Marcelle D. Shidler, Patrick G. Sullivan
Nutrients. 2022 Apr 13; 14(8):1619
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Blueberry anthocyanin intake attenuates the postprandial cardiometabolic effect of an energy-dense food challenge: results from a double blind, randomized controlled trial in metabolic syndrome participants

Peter J Curtis, Lindsey Berends, Vera van der Velpen, Amy Jennings, Laura Haag, Preeti Chandra, Colin D Kay, Eric B Rimm, Aedín Cassidy
Clin Nutr. 2022 Jan 1;41(1):165-176.
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Blueberry intervention improves metabolic syndrome risk factors: systematic review and meta-analysis

Marina Fernandes Carvalho, Ana Beatriz Araújo Lucca, Vítor Rodrigues Ribeiro E Silva, Leandro Roberto de Macedo, Maísa Silva
Nutr Res. 2021 Jul;91:67-80.
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