Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

Blueberry Supplementation in Midlife for Dementia Risk Reduction

Robert Krikorian, Matthew R. Skelton, Suzanne S. Summer, Marcelle D. Shidler, Patrick G. Sullivan
Nutrients. 2022 Apr 13; 14(8):1619
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Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) study: Rationale, design and baseline characteristics of a randomized control trial of the MIND diet on cognitive decline

Xiaoran Liu, Martha Clare Morris, Klodian Dhana, Jennifer Ventrelle, Kathleen Johnson, Louise Bishop, Chiquia S Hollings, Adrianna Boulin, Nancy Laranjo, Benjamin J Stubbs, Xavier Reilly, Vincent J Carey, Yamin Wang, Jeremy D Furtado, Santica M Marcovina, Christy Tangney, Neelum T Aggarwal, Konstantinos Arfanakis, Frank M Sacks, Lisa L Barnes
Contemp Clin Trials. 2021 Mar;102:106270.
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Blueberry phenolics are associated with cognitive enhancement in supplemented healthy older adults

Rutledge GA, Sandhu AK, Miller MG, Edirisinghe I, Burton-Freeman BB, Shukitt-Hale B.
Food Funct. 2021 Jan 7;12(1):107-118.
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Cognitive performance in relation to urinary anthocyanins and their flavonoid-based products following blueberry supplementation in older adults at risk for dementia.

Krikorian R, Kalt W, McDonald JE, Shidler MD, Summer SS, Stein AL.
Journal of Functional Foods, Volume 64, 2020, 103667, ISSN 1756-4646.
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Digestion behavior and antidepressant-like effect promoted by acute administration of blueberry extract on mice

Andreia Gapski, Trilicia M Gomes, Maiara A Bredun, Nayla E Ferreira-Lima, Fabiana Kalyne Ludka, Marilde T Bordignon-Luiz, Vívian Maria Burin
Food Res Int . 2019 Nov;125:108618.
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Blueberries Improve Neuroinflammation and Cognition differentially Depending on Individual Cognitive baseline Status

Barbara Shukitt-Hale, Nopporn Thangthaeng, Marshall G Miller, Shibu M Poulose, Amanda N Carey, Derek R Fisher
J Gerontol A Biol Sci Med Sci. 2019 Jun 18;74(7):977-983.
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Blueberry Supplementation Mitigates Altered Brain Plasticity and Behavior after Traumatic Brain Injury in Rats

Gokul Krishna, Zhe Ying, Fernando Gomez-Pinilla
Mol Nutr Food Res. 2019 Aug;63(15):e1801055.
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The effect of blueberry interventions on cognitive performance and mood: A systematic review of randomized controlled trials

Nikolaj Travica, Nathan M D'Cunha, Nenad Naumovski, Katherine Kent, Duane D Mellor, Joseph Firth, Ekavi N Georgousopoulou, Olivia M Dean, Amy Loughman, Felice Jacka, Wolfgang Marx
Brain Behav Immun . 2020 Mar;85:96-105.
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Cognitive Improving Effects by Highbush Blueberry (Vaccinium crymbosum L.) Vinegar on Scopolamine-Induced Amnesia Mice Model

Seong Min Hong, Kyong Hee Soe, Taek Hwan Lee, In Sook Kim, Young Min Lee, Beong Ou Lim
J Agric Food Chem . 2018 Jan 10;66(1):99-107.
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