Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

Cognitive response to fish oil, blueberry, and combined supplementation in older adults with subjective cognitive impairment

Robert K McNamara, Wilhelmina Kalt, Marcelle D Shidler, Jane McDonald, Suzanne S Summer, Amanda L Stein, Amanda N Stover, Robert Krikorian
Neurobiol Aging. 2018 Apr;64:147-156.
Read More

Blueberry Phenolics Reduce Gastrointestinal Infection of Patients with Cerebral Venous Thrombosis by Improving Depressant-Induced Autoimmune Disorder via miR-155-Mediated Brain-Derived Neurotrophic Factor

Ning Xu, Hao Meng, Tianyi Liu, Yingli Feng, Yuan Qi, Donghuan Zhang, Honglei Wang
Front Pharmacol . 2017 Nov 27;8:853.
Read More

Blueberry supplementation attenuates microglia activation and increases neuroplasticity in mice consuming a high-fat diet

Amanda N Carey, Kelsea R Gildawie, Abigail Rovnak, Nopporn Thangthaeng, Derek R Fisher, Barbara Shukitt-Hale
Nutr Neurosci. 2019 Apr;22(4):253-263.
Read More

Dietary blueberry improves cognition among older adults in a randomized, double-blind, placebo-controlled trial

Marshall G Miller, Derek A Hamilton, James A Joseph, Barbara Shukitt-Hale
Eur J Nutr. 2018 Apr;57(3):1169-1180.
Read More

Enhanced task-related brain activation and resting perfusion in healthy older adults after chronic blueberry supplementation

Joanna L Bowtell, Zainie Aboo-Bakkar, Myra E Conway, Anna-Lynne R Adlam, Jonathan Fulford
Appl Physiol Nutr Metab . 2017 Jul;42(7):773-779.
Read More

Enhanced neural activation with blueberry supplementation in mild cognitive impairment

Erin L Boespflug, James C Eliassen, Jonathan A Dudley, Marcelle D Shidler, Wilhelmina Kalt, Suzanne S Summer, Amanda L Stein, Amanda N Stover, Robert Krikorian
Nutr Neurosci. 2018 May;21(4):297-305.
Read More

Neurochemical differences in learning and memory paradigms among rats supplemented with anthocyanin-rich blueberry diets and exposed to acute doses of 56 Fe particles

Shibu M Poulose, Bernard M Rabin, Donna F Bielinski, Megan E Kelly, Marshall G Miller, Nopporn Thanthaeng, Barbara Shukitt-Hale
Life Sci Space Res (Amst). 2017 Feb;12:16-23.
Read More

Investigation on the Role of BDNF in the Benefits of Blueberry Extracts for the Improvement of Learning and Memory in Alzheimer’s Disease Mouse Model

Long Tan, Hongpeng Yang, Wei Pang, Haiqiang Li, Wei Liu, Shoudan Sun, Nan Song, Wanqi Zhang, Yugang Jiang
J Alzheimers Dis . 2017;56(2):629-640.
Read More

The Anti-Inflammatory Effects of Blueberries in an Animal Model of Post-Traumatic Stress Disorder (PTSD)

Philip J Ebenezer, C Brad Wilson, Leslie D Wilson, Anand R Nair, Francis J
PLoS One. 2016 Sep 7;11(9):e0160923.
Read More