Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

Protective Effects of Blueberry Anthocyanins against H 2 O 2-Induced Oxidative Injuries in Human Retinal Pigment Epithelial Cells

Wu-Yang Huang, Han Wu, Da-Jing Li, Jiang-Feng Song, Ya-Dong Xiao, Chun-Quan Liu, Jian-Zhong Zhou, Zhong-Quan Sui
J Agric Food Chem . 2018 Feb 21;66(7):1638-1648.
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Effects of blueberry and cranberry consumption on type 2 diabetes glycemic control: A systematic review

Daniela Mayumi Usuda Prado Rocha, Ana Paula Silva Caldas, Bárbara Pereira da Silva, Helen Hermana Miranda Hermsdorff, Rita de Cássia Gonçalves Alfenas
Crit Rev Food Sci Nutr . 2019;59(11):1816-1828.
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Blueberry Supplementation Influences the Gut Microbiota, Inflammation, and Insulin Resistance in High-Fat-Diet-Fed Rats

Sunhye Lee, Katherine I Keirsey, Rebecca Kirkland, Zachary I Grunewald, Joan G Fischer, Claire B de La Serre
J Nutr . 2018 Feb 1;148(2):209-219.
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Dual action of highbush blueberry proanthocyanidins on Aggregatibacter actinomycetemcomitans and the host inflammatory response

Amel Ben Lagha, Geneviève LeBel, Daniel Grenier
BMC Complement Altern Med . 2018 Jan 10;18(1):10.
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Cognitive Improving Effects by Highbush Blueberry (Vaccinium crymbosum L.) Vinegar on Scopolamine-Induced Amnesia Mice Model

Seong Min Hong, Kyong Hee Soe, Taek Hwan Lee, In Sook Kim, Young Min Lee, Beong Ou Lim
J Agric Food Chem . 2018 Jan 10;66(1):99-107.
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Beyond Conventional Medicine – a Look at Blueberry, a Cancer-Fighting Superfruit

Kristoffer T Davidson, Ziwen Zhu, Dean Balabanov, Lei Zhao, Mark R Wakefield, Qian Bai, Yujiang Fang
Pathol Oncol Res . 2018 Oct;24(4):733-738.
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Blueberry Metabolites Attenuate Lipotoxicity-Induced Endothelial Dysfunction

Divya Bharat, Rafaela Ramos Mororo Cavalcanti, Chrissa Petersen, Nathan Begaye, Brett Ronald Cutler, Marcella Melo Assis Costa, Renata Kelly Luna Gomes Ramos, Marina Ramos Ferreira, Youyou Li, Leena P Bharath, Emma Toolson, Paul Sebahar, Ryan E Looper, Thunder Jalili, Namakkal S Rajasekaran, Zhenquan Jia, J David Symons, Pon Velayutham Anandh Babu
Mol Nutr Food Res . 2018 Jan;62(2):10.1002/mnfr.201700601.
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Cognitive response to fish oil, blueberry, and combined supplementation in older adults with subjective cognitive impairment

Robert K McNamara, Wilhelmina Kalt, Marcelle D Shidler, Jane McDonald, Suzanne S Summer, Amanda L Stein, Amanda N Stover, Robert Krikorian
Neurobiol Aging. 2018 Apr;64:147-156.
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Blueberry Phenolics Reduce Gastrointestinal Infection of Patients with Cerebral Venous Thrombosis by Improving Depressant-Induced Autoimmune Disorder via miR-155-Mediated Brain-Derived Neurotrophic Factor

Ning Xu, Hao Meng, Tianyi Liu, Yingli Feng, Yuan Qi, Donghuan Zhang, Honglei Wang
Front Pharmacol . 2017 Nov 27;8:853.
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Blueberry supplementation attenuates oxidative stress within monocytes and modulates immune cell levels in adults with metabolic syndrome: a randomized, double-blind, placebo-controlled trial

Anand R Nair, Nithya Mariappan, April J Stull, Joseph Francis
Food Funct . 2017 Nov 15;8(11):4118-4128.
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