Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

Comparison of Blueberry ( Vaccinium spp.) and Vitamin C via Antioxidative and Epigenetic Effects in Human

Minju Kim, Hyunkyung Na, Hiroshi Kasai, Kazuaki Kawai, Yun-Shan Li, Mihi Yang
J Cancer Prev . 2017 Sep;22(3):174-181.
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Blueberry and malvidin inhibit cell cycle progression and induce mitochondrial-mediated apoptosis by abrogating the JAK/STAT-3 signalling pathway

Abdul Basit Baba, Ramesh Nivetha, Indranil Chattopadhyay, Siddavaram Nagini
Food Chem Toxicol . 2017 Nov;109(Pt 1):534-543.
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Blueberry as a Potential Radiosensitizer for Treating Cervical Cancer

Kristoffer T Davidson, Ziwen Zhu, Qian Bai, Huaping Xiao, Mark R Wakefield, Yujiang Fang
Pathol Oncol Res . 2019 Jan;25(1):81-88.
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Blueberry supplementation attenuates microglia activation and increases neuroplasticity in mice consuming a high-fat diet

Amanda N Carey, Kelsea R Gildawie, Abigail Rovnak, Nopporn Thangthaeng, Derek R Fisher, Barbara Shukitt-Hale
Nutr Neurosci. 2019 Apr;22(4):253-263.
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A Brief Review of Blue- and Bilberries’ Potential to Curb Cardio-Metabolic Perturbations: Focus on Diabetes

M Carmen Crespo, Francesco Visioli
Curr Pharm Des . 2017;23(7):983-988.
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Dietary blueberry improves cognition among older adults in a randomized, double-blind, placebo-controlled trial

Marshall G Miller, Derek A Hamilton, James A Joseph, Barbara Shukitt-Hale
Eur J Nutr. 2018 Apr;57(3):1169-1180.
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Enhanced task-related brain activation and resting perfusion in healthy older adults after chronic blueberry supplementation

Joanna L Bowtell, Zainie Aboo-Bakkar, Myra E Conway, Anna-Lynne R Adlam, Jonathan Fulford
Appl Physiol Nutr Metab . 2017 Jul;42(7):773-779.
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The Combination of Blueberry Juice and Probiotics Ameliorate Non-Alcoholic Steatohepatitis (NASH) by Affecting SREBP-1c/PNPLA-3 Pathway via PPAR-α

Tingting Ren, Juanjuan Zhu, Lili Zhu, Mingliang Cheng
Nutrients . 2017 Feb 27;9(3):198.
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Enhanced neural activation with blueberry supplementation in mild cognitive impairment

Erin L Boespflug, James C Eliassen, Jonathan A Dudley, Marcelle D Shidler, Wilhelmina Kalt, Suzanne S Summer, Amanda L Stein, Amanda N Stover, Robert Krikorian
Nutr Neurosci. 2018 May;21(4):297-305.
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Comparison of phytochemical profiles, antioxidant and cellular antioxidant activities of different varieties of blueberry (Vaccinium spp.)

Huailing Wang, Xinbo Guo, Xiaodan Hu, Tong Li, Xiong Fu, Rui Hai Liu
Food Chem . 2017 Feb 15;217:773-781.
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