Scientific Research

The U.S. Highbush Blueberry Council (USHBC) funds research studies that are grounded in sound science, use rigorous methodology, and are conducted by autonomous researchers at well-established institutions. All published research is submitted to peer-reviewed journals by the researcher, independent of the USHBC.

Explore the full overview of research specifically funded by the USHBC, and examine the full body of evidence on blueberry science by browsing the research topics below.

The beneficial effects of fruit polyphenols on brain aging

Francis C Lau, Barbara Shukitt-Hale, James A Joseph
Neurobiol Aging . 2005 Dec;26 Suppl 1:128-32.
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Blueberry- and spirulina-enriched diets enhance striatal dopamine recovery and induce a rapid, transient microglia activation after injury of the rat nigrostriatal dopamine system

Ingrid Strömberg, Carmelina Gemma, Jennifer Vila, Paula C Bickford
Exp Neurol . 2005 Dec;196(2):298-307.
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Effect of lyophilised Vaccinium berries on memory, anxiety and locomotion in adult rats

Maria Rosana Ramirez, Ivan Izquierdo, Maria do Carmo Bassols Raseira, José Angelo Zuanazzi, Daniela Barros, Amélia Teresinha Henriques
Pharmacol Res . 2005 Dec;52(6):457-62.
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The effects of antioxidants in the senescent auditory cortex

C de Rivera, B Shukitt-Hale, J A Joseph, J R Mendelson
Neurobiol Aging . 2006 Jul;27(7):1035-44.
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Oxidative stress and inflammation in brain aging: nutritional considerations

J A Joseph, B Shukitt-Hale, G Casadesus, D Fisher
Neurochem Res . Jun-Jul 2005;30(6-7):927-35.
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Dietary supplementation with fruit polyphenolics ameliorates age-related deficits in behavior and neuronal markers of inflammation and oxidative stress

Shukitt-Hale, B. Search author for Shukitt-Hale, B. , Galli, R.L., Meterko, V., Carey, A., Bielinski, D.F., McGhie, T., Joseph, J.A.
Age the journal of the American Aging Association, v. 27,.1 pp. 49.
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Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory

Cristina Andres-Lacueva, Barbara Shukitt-Hale, Rachel L Galli, Olga Jauregui, Rosa M Lamuela-Raventos, James A Joseph
Nutr Neurosci . 2005 Apr;8(2):111-20.
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Blueberry extract enhances survival of intraocular hippocampal transplants

Lauren Willis, Paula Bickford, Vandana Zaman, Alfred Moore, Ann-Charlotte Granholm
Cell Transplant . 2005;14(4):213-23. doi: 10.3727/000000005783983142.
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Dietary supplementation with blueberries, spinach, or spirulina reduces ischemic brain damage

Yun Wang, Chen-Fu Chang, Jenny Chou, Hui-Ling Chen, Xiaolin Deng, Brandon K Harvey, Jean Lud Cadet, Paula C Bickford
Exp Neurol . 2005 May;193(1):75-84.
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